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Monogenic and Syndromic Diabetes due to Endoplasmic Reticulum Stress
The endoplasmic reticulum (ER) lies at the crossroads of protein folding, calcium storage, lipid metabolism, and the regulation of autophagy and apoptosis. Accordingly, dysregulation of ER homeostasis leads to β-cell dysfunction in type 1 and type 2 diabetes that ultimately culminates in cell death....
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| Publicado no: | J Diabetes Complications |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7648725/ https://ncbi.nlm.nih.gov/pubmed/32518033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdiacomp.2020.107618 |
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