Загрузка...

Pathologic Endoplasmic Reticulum Stress Mediated by the IRE1 Pathway Contributes to Pre-insulitic Beta Cell Apoptosis in a Virus Induced Rat Model of Type 1 Diabetes

AIMS/HYPOTHESIS: We hypothesized that pathologic ER stress contributes to beta cell death during development of type 1 diabetes. In this study, we investigated the occurrence of beta cell ER stress and the signaling pathways involved during discrete stages of autoimmune diabetes progression. The vir...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Diabetologia
Главные авторы: Yang, Chaoxing, diIorio, Philip, Jurczyk, Agata, O'Sullivan-Murphy, Bryan, Urano, Fumihiko, Bortell, Rita
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845659/
https://ncbi.nlm.nih.gov/pubmed/24121653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-3044-4
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!