Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding

In prokaryotic systems, the initiation phase of protein synthesis is governed by the presence of initiation factors that guide the transition of the small ribosomal subunit (30S) from an unlocked preinitiation complex (30S preIC) to a locked initiation complex (30SIC) upon the formation of a correct...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Fabbretti, Attilio, Schedlbauer, Andreas, Brandi, Letizia, Kaminishi, Tatsuya, Giuliodori, Anna Maria, Garofalo, Raffaella, Ochoa-Lizarralde, Borja, Takemoto, Chie, Yokoyama, Shigeyuki, Connell, Sean R., Gualerzi, Claudio O., Fucini, Paola
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2016
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843482/
https://ncbi.nlm.nih.gov/pubmed/27071098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521156113
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