Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding

In prokaryotic systems, the initiation phase of protein synthesis is governed by the presence of initiation factors that guide the transition of the small ribosomal subunit (30S) from an unlocked preinitiation complex (30S preIC) to a locked initiation complex (30SIC) upon the formation of a correct...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Fabbretti, Attilio, Schedlbauer, Andreas, Brandi, Letizia, Kaminishi, Tatsuya, Giuliodori, Anna Maria, Garofalo, Raffaella, Ochoa-Lizarralde, Borja, Takemoto, Chie, Yokoyama, Shigeyuki, Connell, Sean R., Gualerzi, Claudio O., Fucini, Paola
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843482/
https://ncbi.nlm.nih.gov/pubmed/27071098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521156113
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