Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways

In bacteria, the start site and the reading frame of the messenger RNA are selected by the small ribosomal subunit (30S) when the start codon, typically an AUG, is decoded in the P-site by the initiator tRNA in a process guided and controlled by three initiation factors. This process can be efficien...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: López-Alonso, Jorge P., Fabbretti, Attilio, Kaminishi, Tatsuya, Iturrioz, Idoia, Brandi, Letizia, Gil-Carton, David, Gualerzi, Claudio O., Fucini, Paola, Connell, Sean R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Structural Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389724/
https://ncbi.nlm.nih.gov/pubmed/27986852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1251
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