Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways

In bacteria, the start site and the reading frame of the messenger RNA are selected by the small ribosomal subunit (30S) when the start codon, typically an AUG, is decoded in the P-site by the initiator tRNA in a process guided and controlled by three initiation factors. This process can be efficien...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: López-Alonso, Jorge P., Fabbretti, Attilio, Kaminishi, Tatsuya, Iturrioz, Idoia, Brandi, Letizia, Gil-Carton, David, Gualerzi, Claudio O., Fucini, Paola, Connell, Sean R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389724/
https://ncbi.nlm.nih.gov/pubmed/27986852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1251
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