Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways

In bacteria, the start site and the reading frame of the messenger RNA are selected by the small ribosomal subunit (30S) when the start codon, typically an AUG, is decoded in the P-site by the initiator tRNA in a process guided and controlled by three initiation factors. This process can be efficien...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: López-Alonso, Jorge P., Fabbretti, Attilio, Kaminishi, Tatsuya, Iturrioz, Idoia, Brandi, Letizia, Gil-Carton, David, Gualerzi, Claudio O., Fucini, Paola, Connell, Sean R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389724/
https://ncbi.nlm.nih.gov/pubmed/27986852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1251
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items