טוען...

Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer

Misfolding of the microtubule‐associated protein Tau is a hallmark of Alzheimer disease and several other neurodegenerative disorders. Because of the dynamic nature of the Tau protein, little is known about the changes in Tau structure that occur during misfolding. Here we studied the structural con...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Protein Sci
Main Authors: Akoury, Elias, Mukrasch, Marco D., Biernat, Jacek, Tepper, Katharina, Ozenne, Valery, Mandelkow, Eckhard, Blackledge, Martin, Zweckstetter, Markus
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838641/
https://ncbi.nlm.nih.gov/pubmed/26940799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2911
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