Crucial HSP70 co–chaperone complex unlocks metazoan protein disaggregation

Protein aggregates are the hallmark of stressed and ageing cells, and characterize several pathophysiological states(1,2). Healthy metazoan cells effectively eliminate intracellular protein aggregates(3,4), indicating that efficient disaggregation and/or degradation mechanisms exist. However, metazo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nature
Main Authors: Nillegoda, Nadinath B., Kirstein, Janine, Szlachcic, Anna, Berynskyy, Mykhaylo, Stank, Antonia, Stengel, Florian, Arnsburg, Kristin, Gao, Xuechao, Scior, Annika, Aebersold, Ruedi, Guilbride, D. Lys, Wade, Rebecca C., Morimoto, Richard I., Mayer, Matthias P., Bukau, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830470/
https://ncbi.nlm.nih.gov/pubmed/26245380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14884
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados