Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes

Hsp70 participates in a broad spectrum of protein folding processes extending from nascent chain folding to protein disaggregation. This versatility in function is achieved through a diverse family of J-protein cochaperones that select substrates for Hsp70. Substrate selection is further tuned by tr...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Nillegoda, Nadinath B, Stank, Antonia, Malinverni, Duccio, Alberts, Niels, Szlachcic, Anna, Barducci, Alessandro, De Los Rios, Paolo, Wade, Rebecca C, Bukau, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542770/
https://ncbi.nlm.nih.gov/pubmed/28504929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24560
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