Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives

The Escherichia coli AcrAB-TolC efflux pump is the archetype of the resistance nodulation cell division (RND) exporters from Gram-negative bacteria. Overexpression of RND-type efflux pumps is a major factor in multidrug resistance (MDR), which makes these pumps important antibacterial drug discovery...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Sjuts, Hanno, Vargiu, Attilio V., Kwasny, Steven M., Nguyen, Son T., Kim, Hong-Suk, Ding, Xiaoyuan, Ornik, Alina R., Ruggerone, Paolo, Bowlin, Terry L., Nikaido, Hiroshi, Pos, Klaas M., Opperman, Timothy J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822567/
https://ncbi.nlm.nih.gov/pubmed/26976576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602472113
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items