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Prospective Type 1 and Type 2 Disulfides of Keap1 Protein

Experiments were carried out to detect cysteine residues on human Keap1 protein that may be sensors of oxidative stress that gives rise to changes in the GSH/GSSG redox couple. Human Keap1 protein, at a final concentration of 6 μM, was incubated for two hours in aqueous buffer containing 0.010 M GSH...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Holland, Ryan, Hawkins, Arie E., Eggler, Aimee L., Mesecar, Andrew D., Fabris, Daniele, Fishbein, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821167/
https://ncbi.nlm.nih.gov/pubmed/18729328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800226m
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