A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro

Nephrotoxicity due to drugs and environmental chemicals accounts for significant patient mortality and morbidity, but there is no high throughput in vitro method for predictive nephrotoxicity assessment. We show that primary human proximal tubular epithelial cells (HPTECs) possess characteristics of...

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Bibliografiset tiedot
Julkaisussa:J Am Soc Nephrol
Päätekijät: Adler, Melanie, Ramm, Susanne, Hafner, Marc, Muhlich, Jeremy L., Gottwald, Esther Maria, Weber, Elijah, Jaklic, Alenka, Ajay, Amrendra Kumar, Svoboda, Daniel, Auerbach, Scott, Kelly, Edward J., Himmelfarb, Jonathan, Vaidya, Vishal S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2016
Aiheet:
Basic Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814182/
https://ncbi.nlm.nih.gov/pubmed/26260164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015010060
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