A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro

Nephrotoxicity due to drugs and environmental chemicals accounts for significant patient mortality and morbidity, but there is no high throughput in vitro method for predictive nephrotoxicity assessment. We show that primary human proximal tubular epithelial cells (HPTECs) possess characteristics of...

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Bibliografiska uppgifter
I publikationen:J Am Soc Nephrol
Huvudupphovsmän: Adler, Melanie, Ramm, Susanne, Hafner, Marc, Muhlich, Jeremy L., Gottwald, Esther Maria, Weber, Elijah, Jaklic, Alenka, Ajay, Amrendra Kumar, Svoboda, Daniel, Auerbach, Scott, Kelly, Edward J., Himmelfarb, Jonathan, Vaidya, Vishal S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Nephrology 2016
Ämnen:
Basic Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814182/
https://ncbi.nlm.nih.gov/pubmed/26260164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015010060
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