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A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro

Nephrotoxicity due to drugs and environmental chemicals accounts for significant patient mortality and morbidity, but there is no high throughput in vitro method for predictive nephrotoxicity assessment. We show that primary human proximal tubular epithelial cells (HPTECs) possess characteristics of...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Adler, Melanie, Ramm, Susanne, Hafner, Marc, Muhlich, Jeremy L., Gottwald, Esther Maria, Weber, Elijah, Jaklic, Alenka, Ajay, Amrendra Kumar, Svoboda, Daniel, Auerbach, Scott, Kelly, Edward J., Himmelfarb, Jonathan, Vaidya, Vishal S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814182/
https://ncbi.nlm.nih.gov/pubmed/26260164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015010060
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