Therapeutic Targeting of Casein Kinase 1δ in Breast Cancer

Identification of specific drivers of human cancer is required to instruct the development of targeted therapeutics. Here we demonstrate that CSNK1D is amplified and/or overexpressed in human breast tumors and that CK1δ is a vulnerability of human breast cancer subtypes overexpressing this kinase. S...

詳細記述

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書誌詳細
出版年:Sci Transl Med
主要な著者: Rosenberg, Laura H., Lafite, Marie, Quereda, Victor, Grant, Wayne, Chen, Weimin, Bibian, Mathieu, Noguchi, Yoshihiko, Fallahi, Mohammad, Yang, Chunying, Chang, Jenny C., Roush, William R., Cleveland, John L., Duckett, Derek R.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809734/
https://ncbi.nlm.nih.gov/pubmed/26676609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac8773
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