Therapeutic Targeting of Casein Kinase 1δ in Breast Cancer

Identification of specific drivers of human cancer is required to instruct the development of targeted therapeutics. Here we demonstrate that CSNK1D is amplified and/or overexpressed in human breast tumors and that CK1δ is a vulnerability of human breast cancer subtypes overexpressing this kinase. S...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Rosenberg, Laura H., Lafite, Marie, Quereda, Victor, Grant, Wayne, Chen, Weimin, Bibian, Mathieu, Noguchi, Yoshihiko, Fallahi, Mohammad, Yang, Chunying, Chang, Jenny C., Roush, William R., Cleveland, John L., Duckett, Derek R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809734/
https://ncbi.nlm.nih.gov/pubmed/26676609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac8773
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados