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Therapeutic Targeting of Casein Kinase 1δ in Breast Cancer
Identification of specific drivers of human cancer is required to instruct the development of targeted therapeutics. Here we demonstrate that CSNK1D is amplified and/or overexpressed in human breast tumors and that CK1δ is a vulnerability of human breast cancer subtypes overexpressing this kinase. S...
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| Опубликовано в: : | Sci Transl Med |
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| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4809734/ https://ncbi.nlm.nih.gov/pubmed/26676609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac8773 |
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