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Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy
Lung cancer is one of the most lethal forms of cancer and current chemotherapeutic strategies lack broad specificity and efficacy. Recently, β-lapachone (β-lap) was shown to be highly efficacious in killing non-small cell lung cancer (NSCLC) cells regardless of their p53, cell cycle and caspase stat...
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| Veröffentlicht in: | J Control Release |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4803448/ https://ncbi.nlm.nih.gov/pubmed/25542645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.12.027 |
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