Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy

Lung cancer is one of the most lethal forms of cancer and current chemotherapeutic strategies lack broad specificity and efficacy. Recently, β-lapachone (β-lap) was shown to be highly efficacious in killing non-small cell lung cancer (NSCLC) cells regardless of their p53, cell cycle and caspase stat...

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Bibliografische gegevens
Gepubliceerd in:J Control Release
Hoofdauteurs: Ma, Xinpeng, Huang, Xiumei, Moore, Zachary, Huang, Gang, Kilgore, Jessica A., Wang, Yiguang, Hammer, Suntrea, Williams, Noelle S., Boothman, David A., Gao, Jinming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803448/
https://ncbi.nlm.nih.gov/pubmed/25542645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.12.027
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