P2Y(12) receptor blockade synergizes strongly with nitric oxide and prostacyclin to inhibit platelet activation

AIMS: In vivo platelet function is a product of intrinsic platelet reactivity, modifiable by dual antiplatelet therapy (DAPT), and the extrinsic inhibitory endothelial mediators, nitric oxide (NO) and prostacyclin (PGI(2)), that are powerfully potentiated by P2Y(12) receptor blockade. This implies t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Clin Pharmacol
Prif Awduron: Chan, Melissa V., Knowles, Rebecca B. M., Lundberg, Martina H., Tucker, Arthur T., Mohamed, Nura A., Kirkby, Nicholas S., Armstrong, Paul C. J., Mitchell, Jane A., Warner, Timothy D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Translational Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799935/
https://ncbi.nlm.nih.gov/pubmed/26561399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12826
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg