P2Y(12) receptor blockade synergizes strongly with nitric oxide and prostacyclin to inhibit platelet activation

AIMS: In vivo platelet function is a product of intrinsic platelet reactivity, modifiable by dual antiplatelet therapy (DAPT), and the extrinsic inhibitory endothelial mediators, nitric oxide (NO) and prostacyclin (PGI(2)), that are powerfully potentiated by P2Y(12) receptor blockade. This implies t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Chan, Melissa V., Knowles, Rebecca B. M., Lundberg, Martina H., Tucker, Arthur T., Mohamed, Nura A., Kirkby, Nicholas S., Armstrong, Paul C. J., Mitchell, Jane A., Warner, Timothy D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799935/
https://ncbi.nlm.nih.gov/pubmed/26561399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12826
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados