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Blockade of the purinergic P2Y(12) receptor greatly increases the platelet inhibitory actions of nitric oxide
Circulating platelets are constantly exposed to nitric oxide (NO) released from the vascular endothelium. This NO acts to reduce platelet reactivity, and in so doing blunts platelet aggregation and thrombus formation. For successful hemostasis, platelet activation and aggregation must occur at sites...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785756/ https://ncbi.nlm.nih.gov/pubmed/24003163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218880110 |
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