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IN THE PRESENCE OF STRONG P2Y(12) RECEPTOR BLOCKADE, ASPIRIN PROVIDES LITTLE ADDITIONAL INHIBITION OF PLATELET AGGREGATION

BACKGROUND: Aspirin and antagonists of platelet ADP P2Y(12) receptors are often co-prescribed for protection against thrombotic events. However, blockade of platelet P2Y(12) receptors can inhibit thromboxane A(2) (TXA(2)) dependent pathways of platelet activation independently of aspirin. OBJECTIVES...

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Autors principals: Armstrong, Paul C.J., Leadbeater, Philip D., Chan, Melissa V., Kirkby, Nicholas S., Jakubowski, Joseph A., Mitchell, Jane A., Warner, Timothy D.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064407/
https://ncbi.nlm.nih.gov/pubmed/21143373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.04160.x
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