Newly Formed Reticulated Platelets Undermine Pharmacokinetically Short-Lived Antiplatelet Therapies

OBJECTIVE—: Aspirin together with thienopyridine P2Y(12) inhibitors, commonly clopidogrel, is a cornerstone of antiplatelet therapy. However, many patients receiving this therapy display high on-treatment platelet reactivity, which is a major therapeutic hurdle to the prevention of recurrent thrombo...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Armstrong, Paul C., Hoefer, Thomas, Knowles, Rebecca B., Tucker, Arthur T., Hayman, Melissa A., Ferreira, Plinio M., Chan, Melissa V., Warner, Timothy D.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
Assuntos:
Translational Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405774/
https://ncbi.nlm.nih.gov/pubmed/28279968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308763
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