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Eicosanoids, prostacyclin and cyclooxygenase in the cardiovascular system

Eicosanoids represent a diverse family of lipid mediators with fundamental roles in physiology and disease. Within the eicosanoid superfamily are prostanoids, which are specifically derived from arachidonic acid by the enzyme cyclooxygenase (COX). COX has two isoforms; COX‐1 and COX‐2. COX‐2 is the...

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Publicado en:Br J Pharmacol
Autores principales: Mitchell, Jane A, Kirkby, Nicholas S
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451069/
https://ncbi.nlm.nih.gov/pubmed/29468666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14167
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