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Eicosanoids in platelets and the effect of their modulation by aspirin in the cardiovascular system (and beyond)

Platelets are important players in thrombosis and haemostasis with their function being modulated by mediators in the blood and the vascular wall. Among these, eicosanoids can both stimulate and inhibit platelet reactivity. Platelet Cyclooxygenase (COX)‐1‐generated Thromboxane (TX)A(2) is the primar...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Crescente, Marilena, Menke, Laura, Chan, Melissa V, Armstrong, Paul C, Warner, Timothy D
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451075/
https://ncbi.nlm.nih.gov/pubmed/29512148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14196
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