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Eicosanoids in platelets and the effect of their modulation by aspirin in the cardiovascular system (and beyond)

Platelets are important players in thrombosis and haemostasis with their function being modulated by mediators in the blood and the vascular wall. Among these, eicosanoids can both stimulate and inhibit platelet reactivity. Platelet Cyclooxygenase (COX)‐1‐generated Thromboxane (TX)A(2) is the primar...

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Publicat a:Br J Pharmacol
Autors principals: Crescente, Marilena, Menke, Laura, Chan, Melissa V, Armstrong, Paul C, Warner, Timothy D
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451075/
https://ncbi.nlm.nih.gov/pubmed/29512148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14196
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