Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity

Aggregation and toxicity of the amyloid β-peptide (Aβ) are considered as critical events in the initiation and progression of Alzheimer’s disease (AD). Recent evidence indicated that soluble oligomeric Aβ assemblies exert pronounced toxicity, rather than larger fibrillar aggregates that deposit in t...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Acta Neuropathol
Main Authors: Kumar, Sathish, Wirths, Oliver, Stüber, Kathrin, Wunderlich, Patrick, Koch, Philipp, Theil, Sandra, Rezaei-Ghaleh, Nasrollah, Zweckstetter, Markus, Bayer, Thomas A., Brüstle, Oliver, Thal, Dietmar R., Walter, Jochen
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Berlin Heidelberg 2016
Ábhair:
Original Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789232/
https://ncbi.nlm.nih.gov/pubmed/26898910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1546-0
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla