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Reorientational Dynamics of Amyloid-β from NMR Spin Relaxation and Molecular Simulation

[Image: see text] Amyloid-β (Aβ) aggregation is a hallmark of Alzheimer’s disease. As an intrinsically disordered protein, Aβ undergoes extensive dynamics on multiple length and time scales. Access to a comprehensive picture of the reorientational dynamics in Aβ requires therefore the combination of...

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Detalhes bibliográficos
Publicado no:J Phys Chem Lett
Main Authors: Rezaei-Ghaleh, Nasrollah, Parigi, Giacomo, Zweckstetter, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598774/
https://ncbi.nlm.nih.gov/pubmed/31181936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.9b01050
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