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Phosphorylation Interferes with Maturation of Amyloid-β Fibrillar Structure in the N Terminus

Neurodegeneration is characterized by the ubiquitous presence of modifications in protein deposits. Despite their potential significance in the initiation and progression of neurodegenerative diseases, the effects of posttranslational modifications on the molecular properties of protein aggregates a...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Rezaei-Ghaleh, Nasrollah, Kumar, Sathish, Walter, Jochen, Zweckstetter, Markus
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965556/
https://ncbi.nlm.nih.gov/pubmed/27252381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.728956
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