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Phosphorylation Interferes with Maturation of Amyloid-β Fibrillar Structure in the N Terminus

Neurodegeneration is characterized by the ubiquitous presence of modifications in protein deposits. Despite their potential significance in the initiation and progression of neurodegenerative diseases, the effects of posttranslational modifications on the molecular properties of protein aggregates a...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Rezaei-Ghaleh, Nasrollah, Kumar, Sathish, Walter, Jochen, Zweckstetter, Markus
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965556/
https://ncbi.nlm.nih.gov/pubmed/27252381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.728956
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