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Phosphorylation modifies the molecular stability of β-amyloid deposits

Protein aggregation plays a crucial role in neurodegenerative diseases. A key feature of protein aggregates is their ubiquitous modification by phosphorylation. Little is known, however, about the molecular consequences of phosphorylation of protein aggregates. Here we show that phosphorylation of β...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rezaei-Ghaleh, Nasrollah, Amininasab, Mehriar, Kumar, Sathish, Walter, Jochen, Zweckstetter, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833870/
https://ncbi.nlm.nih.gov/pubmed/27072999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11359
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