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Phosphorylation modifies the molecular stability of β-amyloid deposits

Protein aggregation plays a crucial role in neurodegenerative diseases. A key feature of protein aggregates is their ubiquitous modification by phosphorylation. Little is known, however, about the molecular consequences of phosphorylation of protein aggregates. Here we show that phosphorylation of β...

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Publicat a:Nat Commun
Autors principals: Rezaei-Ghaleh, Nasrollah, Amininasab, Mehriar, Kumar, Sathish, Walter, Jochen, Zweckstetter, Markus
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833870/
https://ncbi.nlm.nih.gov/pubmed/27072999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11359
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