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Phosphorylation modifies the molecular stability of β-amyloid deposits

Protein aggregation plays a crucial role in neurodegenerative diseases. A key feature of protein aggregates is their ubiquitous modification by phosphorylation. Little is known, however, about the molecular consequences of phosphorylation of protein aggregates. Here we show that phosphorylation of β...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Rezaei-Ghaleh, Nasrollah, Amininasab, Mehriar, Kumar, Sathish, Walter, Jochen, Zweckstetter, Markus
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833870/
https://ncbi.nlm.nih.gov/pubmed/27072999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11359
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