Novel Phosphorylation-State Specific Antibodies Reveal Differential Deposition of Ser26 Phosphorylated Aβ Species in a Mouse Model of Alzheimer’s Disease

Aggregation and deposition of amyloid-β (Aβ) peptides in extracellular plaques and in the cerebral vasculature are prominent neuropathological features of Alzheimer’s disease (AD) and closely associated with the pathogenesis of AD. Amyloid plaques in the brains of most AD patients and transgenic mou...

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Bibliographic Details
Published in:Front Mol Neurosci
Main Authors: Kumar, Sathish, Kapadia, Akshay, Theil, Sandra, Joshi, Pranav, Riffel, Florian, Heneka, Michael T., Walter, Jochen
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844098/
https://ncbi.nlm.nih.gov/pubmed/33519377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.619639
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