Novel Phosphorylation-State Specific Antibodies Reveal Differential Deposition of Ser26 Phosphorylated Aβ Species in a Mouse Model of Alzheimer’s Disease

Aggregation and deposition of amyloid-β (Aβ) peptides in extracellular plaques and in the cerebral vasculature are prominent neuropathological features of Alzheimer’s disease (AD) and closely associated with the pathogenesis of AD. Amyloid plaques in the brains of most AD patients and transgenic mou...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Kumar, Sathish, Kapadia, Akshay, Theil, Sandra, Joshi, Pranav, Riffel, Florian, Heneka, Michael T., Walter, Jochen
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844098/
https://ncbi.nlm.nih.gov/pubmed/33519377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.619639
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