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Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer’s-like mouse models

The deposition of neurotoxic amyloid-β (Aβ) peptides in extracellular plaques in the brain parenchyma is one of the most prominent neuropathological features of Alzheimer’s disease (AD), and considered to be closely related to the pathogenesis of this disease. A number of recent studies demonstrate...

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Detalles Bibliográficos
Publicado en:Acta Neuropathol Commun
Main Authors: Kumar, Sathish, Lemere, Cynthia A., Walter, Jochen
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388542/
https://ncbi.nlm.nih.gov/pubmed/32727580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00959-w
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