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Phosphorylation of amyloid beta (Aβ) peptides – A trigger for formation of toxic aggregates in Alzheimer's disease

Alzheimer's disease (AD) is the most common form of dementia and associated with the progressive accumulation of amyloid β-peptides (Aβ) in form of extracellular amyloid plaques in the human brain. A critical role of Aβ in the pathogenesis of AD is strongly supported by gene mutations that caus...

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Autors principals: Kumar, Sathish, Walter, Jochen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184981/
https://ncbi.nlm.nih.gov/pubmed/21869458
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