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Aging in Down syndrome and the Development of Alzheimer's disease Neuropathology
Chromosome 21, triplicated in Down Syndrome, contains several genes that are thought to play a critical role in the development of AD neuropathology. The overexpression of the gene for the amyloid precursor protein (APP), on chromosome 21, leads to early onset beta-amyloid (Aβ) plaques in DS. In add...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Curr Alzheimer Res |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4948181/ https://ncbi.nlm.nih.gov/pubmed/26651341 |
| Ετικέτες: |
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