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Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome

INTRODUCTION: Microglial cells play an important role in the development of Alzheimer's disease (AD). People with Down syndrome (DS) inevitably develop AD neuropathology (DSAD) by 40 years of age. We characterized the distribution of different microglial phenotypes in the brains of people with...

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Vydáno v:Alzheimers Dement (Amst)
Hlavní autoři: Martini, Alessandra C., Helman, Alex M., McCarty, Katie L., Lott, Ira T., Doran, Eric, Schmitt, Frederick A., Head, Elizabeth
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560512/
https://ncbi.nlm.nih.gov/pubmed/33088896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12113
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