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Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome

INTRODUCTION: Microglial cells play an important role in the development of Alzheimer's disease (AD). People with Down syndrome (DS) inevitably develop AD neuropathology (DSAD) by 40 years of age. We characterized the distribution of different microglial phenotypes in the brains of people with...

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Publicado en:Alzheimers Dement (Amst)
Main Authors: Martini, Alessandra C., Helman, Alex M., McCarty, Katie L., Lott, Ira T., Doran, Eric, Schmitt, Frederick A., Head, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560512/
https://ncbi.nlm.nih.gov/pubmed/33088896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12113
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