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Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer’s disease and transgenic mouse models

In Alzheimer’s disease (AD) a variety of amyloid β-peptides (Aβ) are deposited in the form of extracellular diffuse and neuritic plaques (NP), as well as within the vasculature. The generation of Aβ from its precursor, the amyloid precursor protein (APP), is a highly complex procedure that involves...

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Publicat a:Acta Neuropathol Commun
Autors principals: Reinert, Jochim, Richard, Bernhard C., Klafki, Hans W., Friedrich, Beate, Bayer, Thomas A., Wiltfang, Jens, Kovacs, Gabor G., Ingelsson, Martin, Lannfelt, Lars, Paetau, Anders, Bergquist, Jonas, Wirths, Oliver
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784385/
https://ncbi.nlm.nih.gov/pubmed/26955942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0294-7
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