Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer’s disease and transgenic mouse models

In Alzheimer’s disease (AD) a variety of amyloid β-peptides (Aβ) are deposited in the form of extracellular diffuse and neuritic plaques (NP), as well as within the vasculature. The generation of Aβ from its precursor, the amyloid precursor protein (APP), is a highly complex procedure that involves...

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Publicado en:Acta Neuropathol Commun
Autores principales: Reinert, Jochim, Richard, Bernhard C., Klafki, Hans W., Friedrich, Beate, Bayer, Thomas A., Wiltfang, Jens, Kovacs, Gabor G., Ingelsson, Martin, Lannfelt, Lars, Paetau, Anders, Bergquist, Jonas, Wirths, Oliver
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784385/
https://ncbi.nlm.nih.gov/pubmed/26955942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0294-7
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