Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer’s disease and transgenic mouse models

In Alzheimer’s disease (AD) a variety of amyloid β-peptides (Aβ) are deposited in the form of extracellular diffuse and neuritic plaques (NP), as well as within the vasculature. The generation of Aβ from its precursor, the amyloid precursor protein (APP), is a highly complex procedure that involves...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Acta Neuropathol Commun
Auteurs principaux: Reinert, Jochim, Richard, Bernhard C., Klafki, Hans W., Friedrich, Beate, Bayer, Thomas A., Wiltfang, Jens, Kovacs, Gabor G., Ingelsson, Martin, Lannfelt, Lars, Paetau, Anders, Bergquist, Jonas, Wirths, Oliver
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784385/
https://ncbi.nlm.nih.gov/pubmed/26955942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0294-7
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires