N-truncated Aβ(4–x) peptides in sporadic Alzheimer’s disease cases and transgenic Alzheimer mouse models

BACKGROUND: The deposition of neurotoxic amyloid-β (Aβ) peptides in plaques in the brain parenchyma and in cerebral blood vessels is considered to be a key event in Alzheimer’s disease (AD) pathogenesis. Although the presence and impact of full-length Aβ peptides such as Aβ(1–40) and Aβ(1–42) have b...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Alzheimers Res Ther
Autori principali: Wirths, Oliver, Walter, Susanne, Kraus, Inga, Klafki, Hans W., Stazi, Martina, Oberstein, Timo J., Ghiso, Jorge, Wiltfang, Jens, Bayer, Thomas A., Weggen, Sascha
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628465/
https://ncbi.nlm.nih.gov/pubmed/28978359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0309-z
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi