The kinase activity of PKR represses inflammasome activity

The protein kinase R (PKR) functions in the antiviral response by controlling protein translation and inflammatory cell signaling pathways. We generated a transgenic, knock-in mouse in which the endogenous PKR is expressed with a point mutation that ablates its kinase activity. This novel animal all...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Res
Main Authors: Yim, Howard CH, Wang, Die, Yu, Liang, White, Christine L, Faber, Pieter W, Williams, Bryan RG, Sadler, Anthony J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783464/
https://ncbi.nlm.nih.gov/pubmed/26794869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.11
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker