Interferon-inducible antiviral effectors

Por Sadler, Anthony J., Williams, Bryan R. G.
Publicado em 2008

An Antiviral Response Directed by PKR Phosphorylation of the RNA Helicase A

Por Sadler, Anthony J., Latchoumanin, Olivier, Hawkes, David, Mak, Johnson, Williams, Bryan R. G.
Publicado em 2009

The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation

Por Dou, Yu, Yim, Howard CH, Kirkwood, Carl D, Williams, Bryan RG, Sadler, Anthony J
Publicado no EMBO J (2017)

Protein Kinase R-dependent Regulation of Interleukin-10 in Response to Double-stranded RNA

Por Chakrabarti, Arindam, Sadler, Anthony J., Kar, Niladri, Young, Howard A., Silverman, Robert H., Williams, Bryan R. G.
Publicado em 2008

Auto-phosphorylation Represses Protein Kinase R Activity

Por Wang, Die, de Weerd, Nicole A., Willard, Belinda, Polekhina, Galina, Williams, Bryan R. G., Sadler, Anthony J.
Publicado no Sci Rep (2017)

The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

Por Dickerman, Benjamin K., White, Christine L., Kessler, Patricia M., Sadler, Anthony J., Williams, Bryan R.G., Sen, Ganes C.
Publicado no FEBS J (2015)

The kinase activity of PKR represses inflammasome activity

Por Yim, Howard CH, Wang, Die, Yu, Liang, White, Christine L, Faber, Pieter W, Williams, Bryan RG, Sadler, Anthony J
Publicado no Cell Res (2016)

Modified vaccinia virus Ankara can activate NF-κB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of vir...

Por Lynch, Heather E., Ray, Caroline A., Oie, Katrina L., Pollara, Justin J., Petty, Ian T. D., Sadler, Anthony J., Williams, Bryan R. G., Pickup, David J.
Publicado em 2009

Promyelocytic Leukemia Zinc Finger Protein Regulates Interferon-Mediated Innate Immunity

Por Xu, Dakang, Holko, Michelle, Sadler, Anthony J., Scott, Bernadette, Higashiyama, Shigeki, Berkofsky-Fessler, Windy, McConnell, Melanie J., Pandolfi, Pier Paolo, Licht, Jonathan D., Williams, Bryan R.G.
Publicado em 2009

Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly

Por Beckham, Simone A., Brouwer, Jason, Roth, Anna, Wang, Die, Sadler, Anthony J., John, Matthias, Jahn-Hofmann, Kerstin, Williams, Bryan R. G., Wilce, Jacqueline A., Wilce, Matthew C. J.
Publicado em 2013

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling

Por Barakat, Badia, Yu, Liang, Lo, Camden, Vu, Duc, De Luca, Elisabetta, Cain, Jason E, Martellotto, Luciano G, Dedhar, Shoukat, Sadler, Anthony J, Wang, Die, Watkins, D Neil, Hannigan, Gregory E
Publicado em 2013

Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling

Por Barakat, Badia, Yu, Liang, Lo, Camden, Vu, Duc, De Luca, Elisabetta, Cain, Jason E, Martellotto, Luciano G, Dedhar, Shoukat, Sadler, Anthony J, Wang, Die, Neil Watkins, D, Hannigan, Gregory E
Publicado em 2013

The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53

Por Szczepny, Anette, Carey, Kirstyn, McKenzie, Lisa, Jayasekara, W. Samantha N., Rossello, Fernando, Gonzalez-Rajal, Alvaro, McCaw, Andrew S., Popovski, Dean, Wang, Die, Sadler, Anthony J., Mahar, Annabelle, Russell, Prudence A., Wright, Gavin, McCloy, Rachael A., Garama, Daniel J., Gough, Daniel J., Baylin, Stephen B., Burgess, Andrew, Cain, Jason E., Watkins, D. Neil
Publicado no Oncogene (2018)

BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs

Por Sadler, Anthony J., Rossello, Fernando J., Yu, Liang, Deane, James A., Yuan, Xiangliang, Wang, Die, Irving, Aaron T., Kaparakis-Liaskos, Maria, Gantier, Michael P., Ying, Hangjie, Yim, Howard C. H., Hartland, Elizabeth L., Notini, Amanda J., de Boer, Suzan, White, Stefan J., Mansell, Ashley, Liu, Jun-Ping, Watkins, D. Neil, Gerondakis, Steve, Williams, Bryan R. G., Xu, Dakang
Publicado no Proc Natl Acad Sci U S A (2015)