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The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

The murine double-stranded RNA-binding protein RAX and the human homolog PACT were originally characterized as activators of protein kinase R (PKR). Mice deficient in RAX show reproductive and developmental defects, including reduced body size, craniofacial defects and anterior pituitary hypoplasia....

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Dickerman, Benjamin K., White, Christine L., Kessler, Patricia M., Sadler, Anthony J., Williams, Bryan R.G., Sen, Ganes C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715520/
https://ncbi.nlm.nih.gov/pubmed/26414443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13533
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