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BIOCHEMICAL ANALYSIS OF PKR ACTIVATION BY PACT
Many extracellular stresses cause inhibition of translation initiation by triggering phosphorylation of the initiation factor, eIF-2α. A major protein kinase responsible for this phosphorylation is PKR, a latent kinase which itself needs activation by autophosphorylation. In stressed cells, this act...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766932/ https://ncbi.nlm.nih.gov/pubmed/19580324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900433y |
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