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Molecular basis for PKR activation by PACT or dsRNA
The mammalian protein kinase PKR is a critical component of the innate immune response against virus infection. Its cellular actions are mediated by modulating cell signaling and translational regulation. To be enzymatically active, latent PKR needs to be activated by binding to one of its activator...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1502496/ https://ncbi.nlm.nih.gov/pubmed/16785445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602317103 |
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