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The Human dsRNA binding protein PACT is unable to functionally substitute for the Drosophila dsRNA binding protein R2D2

The dsRNA binding protein (dsRBP) PACT was first described as an activator of the dsRNA dependent protein kinase PKR in response to stress signals.  Additionally, it has been identified as a component of the small RNA processing pathway.  A role for PACT in this pathway represents an important inter...

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Main Authors: Dickerman, Benjamin K, McDonald, Jocelyn A, Sen, Ganes C
Formato: Artigo
Idioma:Inglês
Publicado: F1000Research 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962003/
https://ncbi.nlm.nih.gov/pubmed/24715958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-220.v2
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