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The Role of PACT in Mediating Gene Induction, PKR Activation, and Apoptosis in Response to Diverse Stimuli

PACT, the protein activator of the double-stranded (ds)RNA-activated protein kinase (PKR) has been shown to strongly interact with and activate PKR in cultured cells and in vitro. To further analyze the functions of PACT we have recently generated PACT knockout (KO) mice and described several develo...

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Detalhes bibliográficos
Main Authors: Marques, Joao T., White, Christine L., Peters, Gregory A., Williams, Bryan R.G., Sen, Ganes C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965581/
https://ncbi.nlm.nih.gov/pubmed/18729737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2007.0006
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