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Essential Role of PACT-Mediated PKR Activation in Tunicamycin-induced Apoptosis
Cellular stresses such as disruption of calcium homeostasis, inhibition of protein glycosylation, and reduction of disulfide bonds result in accumulation of misfolded proteins in the endoplasmic reticulum (ER) and lead to cell death by apoptosis. Tunicamycin, which is an inhibitor of protein glycosy...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026198/ https://ncbi.nlm.nih.gov/pubmed/19007793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.068 |
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