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Auto-phosphorylation Represses Protein Kinase R Activity

The central role of protein kinases in controlling disease processes has spurred efforts to develop pharmaceutical regulators of their activity. A rational strategy to achieve this end is to determine intrinsic auto-regulatory processes, then selectively target these different states of kinases to r...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Wang, Die, de Weerd, Nicole A., Willard, Belinda, Polekhina, Galina, Williams, Bryan R. G., Sadler, Anthony J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345052/
https://ncbi.nlm.nih.gov/pubmed/28281686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44340
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