The regulation of AMP-activated protein kinase by phosphorylation.

The AMP-activated protein kinase (AMPK) cascade is activated by an increase in the AMP/ATP ratio within the cell. AMPK is regulated allosterically by AMP and by reversible phosphorylation. Threonine-172 within the catalytic subunit (alpha) of AMPK (Thr(172)) was identified as the major site phosphor...

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Bibliografiske detaljer
Main Authors: Stein, S C, Woods, A, Jones, N A, Davison, M D, Carling, D
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220775/
https://ncbi.nlm.nih.gov/pubmed/10642499
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